Progressive retinal atrophy, PRA1 is an adult-onset, inherited eye disease affecting dogs. Progressive retinal atrophy, PRA1 occurs as a result of degeneration of the rod type photoreceptor cells of the retina, which are important for vision in low light. Dogs affected with progressive retinal atrophy, PRA1 typically present between 4 to 6 years of age with poor vision in dim light. On a veterinary eye exam affected dogs have changes in reflectivity and appearance of a structure behind the retina called the tapetum as well as thinning of the retinal blood vessels, signifying decreased blood flow to the retina. Progressive retinal atrophy, PRA1 is slowly progressive and some affected dogs maintain vision in daylight for many years, sometimes for the remainder of their life.

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