Spinal dysraphism is an inherited developmental disease affecting weimaraners. Affected dogs have abnormal development of the spinal cord resulting in neurologic disease. Clinical signs range from mild to severe depending upon the severity and location of spinal cord defects. Affected dogs typically present at 4 to 6 weeks of age with a “bunny hopping” gait, a crouching, wide-based stance, and abnormal reflexes in the hind limbs. Abnormal hair growth along the back, curvature of the spine, malformed sternum and kinked tails have also been reported. Clinical signs of the disease do not progress in severity with age.

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