Hereditary footpad hyperkeratosis is an inherited disease of footpads affecting dogs. Affected dogs typically present around 4 to 5 months of age with hard, thickened footpads. With time, the abnormal footpads often develop deep cracks predisposing affected dogs to foot infections, significant pain and lameness. Thick, horny growths also commonly develop around the rim of the footpads. Toenails of affected dogs are harder than normal and appear to grow faster. In addition, some affected dogs may display a duller and softer hair coat than normal littermates.

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