Chondrodysplasia is an inherited disease affecting dogs. Affected dogs are unable to synthesize a protein important for cartilage and bone development resulting in dwarfism. Symptoms can include short bowed legs, shortening of outer digits, “knock-knee” appearance, hip dysplasia and muscle atrophy of hind limbs. On average, limbs of affected adults are about 10 cm shorter than normal dogs. Due to abnormal bone alignment at joints, dogs with this condition may be predisposed to arthritis as they age.

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