Epidermolytic hyperkeratosis is an inherited condition of the skin affecting dogs. Affected dogs can display sloughing and blistering of the skin with rubbing as may occur when drying the pups after birth. As the dog matures, the skin becomes flaky and dark (hyperpigmented), especially in locations on the body where two skin areas may touch or rub together. The footpads, claws, teeth and hair of affected dogs are typically normal.

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